Remarks: We will only be able to guess, how many lives may have been lost due to health bureaucrats in Australia believing they knew better, causing them to interfere in the sanctity of the Doctor/patient relationship and taking away Australian doctors’ freedoms to prescribe HCQ to their COVID patients if they thought (as thousands of medical specialists around the world believe) that it might help save their patients lives. FULL STORY HERE: https://www.4cmitv.com/2020/09/16/2020-sep-14-effect-of-combination-therapy-of-hydroxychloroquine-and-azithromycin-on-mortality-in-covid%e2%80%9019-patients-73-reduction-in-death/
Craig Kelly MP: LATEST (PEER-REVIEWED) HYDROXYCHLOROQUINE STUDY
Lauriola et al., Clinical and Translational Science, doi:10.1111/cts.12860 (Peer Reviewed)
Title : ‘Effect of combination therapy of hydroxychloroquine and azithromycin on mortality in COVID‐19 patients’
Retrospective study from Italy of 377 patients, found 73% reduction in death for Covid patients treated with HCQ+AZ. Mean age 71.8. No serious adverse events.
And we are only left to speculate how much better the results would have been if zinc was included in the treatment.
ASCPT online library 10.1111/cts.12860
The anti-hydroxychloroquine club, lead by Labor’s Chris Bowen (and their cheer-squads in the media, starting with the ABC) now have egg all over their faces. It’s well past time they apologised and admitted they were fatally wrong, and resigned.
We will only be able to guess, how many lives may have been lost due to health bureaucrats in Australia believing they knew better, causing them to interfere in the sanctity of the Doctor/patient relationship and taking away Australian doctors’ freedoms to prescribe HCQ to their COVID patients if they thought (as thousands of medical specialists around the world believe) that it might help save their patients lives.
History will likely record the banning of HCQ in Australia as one of the greatest medical errors in our nation.
The only question now, is how long the denial of the evidence will continue ?
Effect of combination therapy of hydroxychloroquine and azithromycin on mortality in COVID‐19 patients.
Authors: Marinella Lauriola, Arianna Pani, Giovanbattista Ippoliti, Andrea Mortara, Stefano Milighetti, Marjieh Mazen, Gianluca Perseghin, Daniele Pastori, Paolo Grosso, Francesco Scaglione.
First published: 14 September 2020
Conflicting evidence regarding the use of hydroxychloroquine and azithromycin for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection do exist.
We performed a retrospective single‐center cohort study including 377 consecutive patients admitted for pneumonia related to coronavirus disease (COVID‐19). Of these 297 were in combination treatment, 17 were on hydroxychloroquine alone and 63 did not receive any of these two drugs because of contraindications. The primary endpoint was in‐hospital death.
Mean age was 71.8±13.4 years and 34.2% were women. We recorded 146 deaths: 35 in no treatment, 7 in hydroxychloroquine and 102 in hydroxychloroquine + azithromycin group (log‐rank test for Kaplan‐Meier curve p<0.001).
At multivariable Cox proportional hazard regression analysis, age (hazard ratio [HR] 1.057, 95% confidence interval [CI] 1.035‐1.079, p<0.001), mechanical ventilation/CPAP (HR 2.726, 95%CI 1.823‐4.074, p<0.001), C Reactive Protein above the median (HR 2.191, 95%CI 1.479‐3.246, p<0.001) were directly associated with death, whilst use of hydroxychloroquine + azithromycin (vs. no treatment) (HR 0.265, 95%CI 0.171‐0.412, p<0.001) was inversely associated.
In this study, we found a reduced in‐hospital mortality in patients treated with a combination of hydroxychloroquine and azithromycin after adjustment for comorbidities. A large randomized trial is necessary to confirm these findings.
Original PDF Source: 10.1111/cts.12860
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References [ + ]
|1.||American Society for Clinical Pharmacology and Therapeutics|